The next big thing in medicine for malaria is most likely on your kitchen shelf.
Researchers at the Indian Institute of Science (IISc) in Bangalore are readying for human trials to develop an affordable and non-toxic drug to fight malaria, a disease that strikes about two million Indians every year.The drug will be laced with a component of turmeric, the traditional Indian spice and home remedy also known to have anti-cancer properties.
“The new drug could hit markets in two years,’’ G Padmanabhan, former IISc director and project head told the Hindustan Times in Hyderabad. “There is no need for Phase-1 trials to assess drug toxicity, since turmeric is eaten raw.’’
With Rs one crore funding from the department of biotechnology, the Phase-II human trials are set to begin this year on 100 volunteers each at the malaria-hotspots of Rourkela in Orissa and Jabalpur in Madhya Pradesh. Half of the reported malaria deaths in India are from Orissa, and 95 per cent Indians live in malaria-risk areas.
After successful trials on mice, the team announced last year that curcumin, the ingredient that gives turmeric its yellow colour, contains anti-malarial properties that could be developed in a drug. A drug combo of curcumin obtained from turmeric and an artemisinin derivative will be tested on the volunteers. Artemisinin is a widely prescribed Chinese drug considered effective against malaria. But the World Health Organisation says that there is a risk of the malaria-causing parasite developing resistance when artemisinin is used solo.
The next big thing in medicine for malaria is most likely on your kitchen shelf.
Researchers at the Indian Institute of Science (IISc) in Bangalore are readying for human trials to develop an affordable and non-toxic drug to fight malaria, a disease that strikes about two million Indians every year.The drug will be laced with a component of turmeric, the traditional Indian spice and home remedy also known to have anti-cancer properties.
“The new drug could hit markets in two years,’’ G Padmanabhan, former IISc director and project head told the Hindustan Times in Hyderabad. “There is no need for Phase-1 trials to assess drug toxicity, since turmeric is eaten raw.’’
With Rs one crore funding from the department of biotechnology, the Phase-II human trials are set to begin this year on 100 volunteers each at the malaria-hotspots of Rourkela in Orissa and Jabalpur in Madhya Pradesh. Half of the reported malaria deaths in India are from Orissa, and 95 per cent Indians live in malaria-risk areas.
After successful trials on mice, the team announced last year that curcumin, the ingredient that gives turmeric its yellow colour, contains anti-malarial properties that could be developed in a drug. A drug combo of curcumin obtained from turmeric and an artemisinin derivative will be tested on the volunteers. Artemisinin is a widely prescribed Chinese drug considered effective against malaria. But the World Health Organisation says that there is a risk of the malaria-causing parasite developing resistance when artemisinin is used solo.
RSP DGMs promoted as GMsWednesday February 21 2007 10:51 ISTROURKELA:Ten deputy general managers (DGMs) of Rourkela Steel Plant (RSP) were on Tuesday elevated to the rank of general managers (GMs). RSP sources said this is the first time in the last one decade that so many executives have been elevated to the post of GM at one go.Managing Director, B N Singh handed over the promotion orders to the executives. The move came after the Board of Directors of SAIL approved the promotions under its corporate policy. While six of the promoted officers will continue with RSP, four have been transferred with promotion to different SAIL units.
Bhubaneswar, Feb 17 (IANS)At least three people were killed and over 20 injured early Saturday after the bus in which they were travelling fell into a river in Orissa's Keonjhar district.The private bus, carrying about 50 passengers, was going from Angul town to Jamshedpur in the neighbouring state of Jharkhand when it fell into the Baitarani river at Turumunga village in Keonjhar, around 250 km from here.
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"Police and fire fighters have rushed to the spot and rescue operations have been launched," said B.K. Murmu, officer in charge of the Turumunga police station.
Keonjhar (Orissa):At least three persons were killed and around 20 others injured when a bus plunged into the Baitarani river near Kurmanga, about 30 kilometre from Keonjhar on Saturday morning.
The bus was on its way from Angul to Jamshedpur when the mishap occurred at around 0400 hrs, IST, the officer-in-charge of Kurmanga police station, Bijoy Murmu said.
There were between 40 to 50 passengers in the vehicle, he confirmed.Fire brigade personnel had so far retrieved three bodies from the water while around 20 persons had been rescued. Some others had managed to swim to safety as there was not much water in the river.
The rescue operation was on, Murmu said. The injured had been shifted to government hospitals here and at Karanjia.
The cause of the mishap is not known as yet. The vehicle had crashed through the railings before plunging into the water, Murmu added.
Bangalore Lions melt Orissa Steelers BALBIR SINGH Friday, 16 February 2007
CHANDIGARH: Holders Bangalore Lions bounced back into the race for the title with a well-deserved 4-3 verdict over leaders and strong contenders Orissa Steelers in the third edition of the Premier Hockey League being played under lights at the Sector 42 Astroturf Hockey Stadium here on Friday night.
Watched by a goodly crowd, Bangalore Lions fought off a stiff challenge from an equally impressive Orissa Steelers to claim full three points from their crucial encounter. Lions fell in arrears twice but kept up the tempo to level the game and scored twice in the space of two minutes in the third quarter to take the lead. Bangalore Lions increased the lead to 4-2 early in the last quarter, but Orissa played with determination and pulled one back in the very next minute to keep up the fight till the end. However, Bangalore defended stubbornly and made sudden counters to walk away with full honours. Bangalore now have 12 points and move up to third place on the table after eight matches while Orissa still lead the table with 17 points after as many matches.
Orissa displayed controlled aggression with main stress on defence in the first quarter. Marking the rival forwards tightly, they used flanks to make their raids. Forcing their first penalty corner in the 10 th minute, Orissa Stelers forged ahead through skipper Dilip Tirkey, whose powerful hit deflected off Bangalore first-runner Ignace Tirkey's stick and settled in the net. (1-0).
Later, both the teams fought a grim battle to control the midfield and fortunes fluctuated either way. Sunil Ekka missed a sharp chance for Orissa in the 21 st minute and off Bangalore's first short corner in the 23rd minute, Orissa custodian Salman Akbar made a brilliant save to stop Len Aiyappa's flick. But Bangalore kept the pressure up and notched the equalizer in the 30 th minute off their second set-piece drill. Tushar took the push but their South African import Paul Blake fumbled with the stop and ball went to Arjun Halappa at the dotted line and he quickly put Sandeep Michael in possession near the spot. Michael turned around to avoid a defender and found the boards with a smart reverse-stick shot. (1-1).
Within six minutes, Orissa Steelers took the lead once again converting their third and final short corner. Off the 36th minute penalty corner, Dilip Tirkey's direct hit was blocked by Lions' first-runner Ignace Tirkey and ball went to Prabod Tirkey. Prabod miscued the shot but an alert Dilip Tirkey was at hand to bang home their second goal. (2-1) However, the lead was short-lived with Bangalore forcing their third short-corner in the 40 th minute to draw level. Len Aiyappa, who played a superb game in the defence, flicked a powerful grounder that left Orissa custodian Salman Akbar stranded. (2-2).
Thereafter, the lead changed hands as Bangalore made repeated raids on the rival citadel and the sustained pressure yielded results in the 42 nd minute. Following a long corner, Rehan Butt sent a stunning back pass from the right goalline and Ignace Tirkey pulled the ball into the circle and slammed in to make it 3-2. The goal saw Orissa switch into an attacking mode with their midfielders constantly moving up to assist the forwards. They did create some anxious moments for the rival defence but their Argentine star Mario Alamada had a narrow miss when his reverse hit missed the target by inches. They continued to attack and conceded one more goal to a counter attack when Hariprasad gained a penalty corner for Lions in the 58 th minute. Len Aiyappa took the drag flick once again but hit the right vertical and Sandeep Michael pounced on the rebound to tap it home. (4-2).
With a never-say-die spirit, Orissa pulled one back in the very next minute to keep themselves in with a chance. In the 59th minute, Prabodh Tirkey sent a power-packed long ball towards the goal from the midfield and Sunil Ekka stretched his stick to deflect home. (4-3). However, Bangalore held on to the narrow lead and survived anxious moments as Orissa ran out of time to suffer their second defeat.
Sandeep Michael of Bangalore Lions, who scored two opportunistic goals, was adjudged Lion of the day.
Tomorrow's fixtures: Hyderabad Sultans vs Chennai Veerans ( 5p.m.) and Chandigarh Dynamos vs Maratha Warriors ( 7.30 p.m).
Orissa handicrafts’ exhibitionHT CorrespondentBhopal, February 15, 2007
SHOWCASING HANDICRAFTS and paintings of Orissa, Sakuntala Women Chandua Hastashilpa Cooperative Society Limited has organised a handicafts exhibition at Gandhi Bhawan. The exhibition-cum-sale will continue till February 18.
Sponsored by the Development Commissioner (Handicrafts) Ministry of Textiles, the exhibition has displayed colourful products of terracotta, appliqué, stone carving, palm leaf engraving, Dokra castings, wood carvings, shell-work and miniature painting.
“The miniature paintings have shown the folk-tale of Lord Krishna (Krishna-Leela),” said Lingraja Temple, Bhuwaneshwar, temple priest Ajit Mohapatro.
A new item on display are small gift envelopes, with miniature painting on it, which could be used as wall-hanging.Local coordinator Parthasarthy Dubey said the exhibition also has exclusive decoration-cum-usable items and garden umbrellas of Applique art.
BHUBANESWAR: Thousands of devotees early on Friday thronged temples dedicated to Hindu god Shiva across Orissa on the occasion of Shivratri. ...
Orissa to set up VC fund for IT firmsNirmalya Mukherjee / Bhubaneswar February 16, 2007
Taking a leaf out of Karnataka, Orissa is exploring the possibility of setting up a Venture Capital Fund (VCF) for small and medium IT enterprises in the state.
This is in line with plans to set up a National Venture Capital Fund (NVCF) for IT SMEs, which is currently pending with the Planning Commission.
The Karnataka government has already set up a VCF with the Small Industries Development Bank of India (SIDBI) with a corpus of Rs 15 crore to promote the Software Technology Parks of India (STPI). Known as the country's silicon valley, Karnataka is the first state to accept the NVCF proposal and has become a role model for other states.
Currently, Orissa STPI has a catalogue of 100 registered IT/ITeS companies, of which only five per cent are in the big league and the remaining are IT SMEs. State STPI officials said they were aware of the NVCF formation proposal and are already making efforts to establish a state venture capital fund (SVCF).
A highly placed official said, “We are talking to the Orissa government, especially the IT department, on the possibility of setting up a SVCF. This would benefit the 95 per cent IT SMEs operating out of the state.”
Senior officials said matters on those lines are currently being explored into. According to STPI estimates, Orissa's software exports stand at Rs 465 crore and officials are confident that with the surge in IT companies, the exports would cross Rs 650 crore.
Interestingly, 85 per cent of Orissa's software export earnings are from Infosys and Satyam - both long time players. Of late, TCS, Wipro, MindTree and Hexawire are also planning forays into the state. According to STPI estimates, Rs 1000 crore has been invested in the IT/ITeS sector in the state.
India's software exports are pegged at Rs 1,08,000 crore, of which Karnataka alone contributes Rs 37,000 crore followed by Maharashtra and Tamil Nadu. West Bengal and Orissa are in the eigth and ninth positions respectively.
STPI officials are working closely with their counterparts in Karnataka to work out the SVCF model with assistance from the Orissa government. The SIDBI model would work depending on which bank or financial institution the state government would tie up with. The corpus would be determined after detailed discussions.
A STPI official said, “Things are at a nebulous stage. We are trying hard to make things work out soon.” The STPI has requested the Orissa government for three acres to set up technological incubators, which would facilitate IT SMEs. It would be an one umbrella facility with rooms, space common voice and other ready-to-use facilities.
Thousands throng Orissa temples on Shivratri
Posted on : Fri, 16 Feb 2007 07:47:01 GMT Author : Indo Asian News ServiceNews Category :
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Bhubaneswar, Feb 16 Thousands of devotees early Friday thronged temples dedicated to Hindu god Shiva across Orissa on the occasion of Shivratri.
Shivratri is celebrated on the 13th or 14th day of the dark half (Krishna Paksha) of Phalgun (February-March), according to the Hindu calendar. It is widely believed that Shiva, one of the holy trinity along with Vishnu and Brahma, married Parvati on this day.